IMMUNOLOGY

National Immunisation Program Schedule (vaccinations)

Additional Notes for Risk Groups:

  • Pregnant Women: Recommended pertussis vaccination in each pregnancy, ideally between 20-32 weeks, and influenza vaccination at any stage of pregnancy.
  • People with Specified Medical Risk Conditions: Higher risk of complications from infections, requiring additional doses for pneumococcal, meningococcal, influenza, and other vaccines.
  • Refugees and Humanitarian Entrants: Eligible for catch-up vaccines, including hepatitis B, polio, measles-mumps-rubella, HPV, and others depending on age.
  • Immunocompromised Individuals: Additional vaccines or different schedules for pneumococcal, shingles, and meningococcal.

ATSI Specific

Vaccine2 Months (from 6 weeks)4 Months6 Months12 Months18 Months4 Years≥5 Years (Annually)50 Years and Over
Meningococcal B: Bexsero®
ATSI children w specified medical risk conditions
Pneumococcal: Prevenar 13®(WA, NT, SA, Qld)(WA, NT, SA, Qld)✔ Prevenar 13® & Pneumovax 23® (3 doses)
Influenza (age-appropriate)✔ Two doses 1 month apart, then annual✔ One dose annually✔ One dose annually
Hepatitis A: Vaqta® Paediatric(WA, NT, SA, Qld)(WA, NT, SA, Qld)
Shingles (herpes zoster): Shingrix®✔ Administer 2 doses


Vaccines for people with medical risk conditions

based on: https://www.health.gov.au/topics/immunisation/when-to-get-vaccinated/immunisation-for-people-with-medical-risk-conditions?language=und

VaccineEligibility/ConditionsAdditional Information
Pneumococcal– Children under 12 months with specific medical conditions (6 doses over time)
– All people 12 months and over with specific conditions (3 doses)
Free for those at higher risk due to:
– Functional/anatomical asplenia
– Immunocompromising conditions
– Chronic diseases (lung, kidney, heart)
– Premature birth
– Down syndrome
– Specific surgeries (cochlear implants, intracranial shunts)
– CSF leaks
– History of invasive pneumococcal disease
Meningococcal– Children under 12 months with specific medical risk conditions (dose schedule depends on age)
– All people 12 months and over with specific conditions (2 doses of both ACWY and B vaccines)
Free for those at higher risk due to:
– Functional/anatomical asplenia/hyposplenia
– Complement deficiency
– Treatment with eculizumab
Influenza– People aged 6 months and over with medical conditions increasing risk of complications (annual vaccination)Free for those at risk due to:
– Heart disease
– Chronic lung disease
– Chronic neurological conditions
– Impaired immunity
– Haemoglobinopathies
– Diabetes
– Kidney disease
Haemophilus influenzae type b (Hib)– people who are immunocompromised , including people with asplenia and people who have received a haematopoietic stem cell transplant.Free for those eligible under the National Immunisation Program
Shingles (Shingrix)– Immunocompromised people aged 18 years and over with:
– Haematopoietic stem cell transplant
– Solid organ transplant
– Haematological malignancy
– Advanced or untreated HIV
– Free for those previously vaccinated with Zostavax if eligible
– Must wait 12 months between Zostavax and Shingrix
Condition/EligibilityPneumococcalMeningococcalInfluenzaHaemophilus influenzae type b (Hib)Shingles (Shingrix)
Functional or anatomical asplenia/hypospleniaYesYesNoYesNo
Immunocompromising conditionsYes (incl. organ and stem cell transplants, HIV)YesYesYesYes
– stem cell transplant
– solid organ transplant
– HIV
Chronic diseases (lung, kidney, heart)YesNoYesNoNo
Premature birthYesNoNoNoNo
Down syndromeYesNoNoNoNo
Previous invasive pneumococcal diseaseYesNoNoNoNo
Complement deficiencyNoYesNoNoNo
Treatment with eculizumabNoYesNoNoNo
Heart diseaseNoNoYesNoNo
Chronic lung disease (severe asthma)NoNoYesNoNo
Chronic neurological conditionsYes
cochlear implants and intracranial shunts
NoYesNoNo
DiabetesNoNoYesNoNo
Kidney diseaseNoNoYesNoNo
Haematological malignancyNoNoNoNoYes
CSF leaksYesNoNoNoNo

Booster dosing

Vaccinations That Require Booster Doses:

  • Diphtheria
  • Tetanus
  • Whooping Cough (Pertussis)

Diphtheria and Tetanus Vaccinations:

Administered as either:

  • dT (Diphtheria-Tetanus)
  • DTPa (Diphtheria, Tetanus, Pertussis – Whooping Cough)

Tetanus:

  • A serious disease causing severe muscle spasms, particularly in the neck and jaw (lockjaw).
  • Can lead to death in severe cases.

Recommended Booster Dose of Tetanus-Containing Vaccine for Adults:

  • If you are 50 years or older.
  • If you haven’t had a tetanus shot in the last 10 years.
  • If you have a wound more than a minor cut, and your last tetanus vaccine was over 5 years ago.
  • If you’ve previously completed the primary course of 3 doses.

Whooping Cough (Pertussis):

  • A serious disease that can lead to complications such as pneumonia, brain injury, and, in severe cases, death.
  • Especially dangerous for babies, but can affect people of any age.

Who Should Receive a Booster Dose of the Whooping Cough Vaccine:

  • Adults who haven’t had the vaccine in the past 10 years, particularly if:
    • You are 65 years or older.
    • You are in close contact with infants.

Accessing Booster Vaccines:

  • The National Immunisation Program does not cover booster vaccines for adults and seniors.
  • Additional vaccines can be purchased privately.
  • Consult a healthcare professional to determine if you or someone in your care needs additional vaccines.

QLD specific:

  • COVID-19 Updates: Continual updates on COVID-19 vaccination are provided, with the latest information accessible through Queensland Health.
  • Annual Influenza Program: Annual vaccinations recommended for everyone aged 6 months and older to prevent influenza and its complications.
  • Pertussis, Influenza, and COVID-19 Vaccination for Pregnant Women: Pertussis vaccine recommended between 20 and 32 weeks of pregnancy, Influenza vaccine can be administered concurrently but should not be delayed for simultaneous administration.
  • Shingles Vaccination: From November 1, 2023, the Shingrix® vaccine is free under the NIP for adults aged 65 years and older.
  • Hepatitis B Vaccination: Funded for specific high-risk groups under the NIP.
  • Queensland School Immunisation Program:

Meningococcal B (MenB) Vaccination Program:

  • A new QLD-funded program targeting the meningococcal B strain, rolling out in early 2024 across schools and primary care providers.
  • Infant and Childhood Program
    • Infants aged 6 weeks to 12 months of age (eligible for vaccination through the Queensland MenB Vaccination Program):
      • 3 doses of Bexsero® menB vaccine (2 dose primary course and one booster dose).
      • These will be administered with other National Immunisation Program (NIP) vaccines at 6 weeks, 4 months and 12 months of age.
    • Children aged between 12 months and less than 2 years of age (eligible for vaccination through the Queensland MenB Vaccination Program)
Age GroupVaccine DoseVaccination TimeAdditional Information
Infants (<12 months)1st Dose6 weeksAdministered with other NIP vaccines
2nd Dose4 monthsAdministered with other NIP vaccines
Booster Dose12 monthsAdministered with other NIP vaccines
Aboriginal and Torres Strait Islander Infants with Medical RisksAdditional Dose6 months
Children (12 months to <2 years)1st DoseStart any time between 12-23 months
2nd DoseMinimum 8 weeks after the 1st dose
  • Adolescent Program
    • Adolescents aged 15 to 19 years inclusive (15-<20 years) (eligible for vaccination through the Queensland MenB Vaccination Program):
      • 2 doses Bexsero® vaccine with a minimal interval of 8 weeks between doses.
    • Students in year 10 will be offered vaccination through the Queensland School Immunisation Program
    • People with specific medical conditions (eligible for vaccination through the National Immunisation Program):
      • People with the following conditions are considered to have an increased risk of invasive meningococcal disease:
      • defects in, or deficiency of, complement components, including factor H, factor D or properdin deficiency
      • people with acquired complement deficiency due to receipt of complement inhibitor therapy (including but not limited to eculizumab or ravulizumab)
      • functional or anatomical asplenia, including sickle cell disease or other haemoglobinopathies, and congenital or acquired asplenia
      • HIV, regardless of disease stage or CD4+ cell count
      • haematopoietic stem cell transplant

Meningococcal B (Bexsero®) vaccination schedule according to the manufacturer’s guidelines:

Prophylactic Paracetamol Recommendations

Due to the increased risk of fever1, prophylactic paracetamol is recommended with every dose of Bexsero in children <2 years of age2

Bexsero recommendations.png

Note: The Australian Immunisation Handbook recommends the prophylactic use of paracetamol with every dose of Bexsero administered to children <2 years of age, regardless of presence of fever. 2 †Or as soon as practicable afterward.2 *ATAGI recommends doses of paracetamol to be given 6 hours apart.2

Bexsero can be given concomitantly with the following vaccine antigens (monovalent or as combination vaccines)

  • Diphtheria, tetanus, acellular pertussis, hepatitis B, inactivated poliomyelitis, Haemophilus influenzae type B
  • Meningococcal group A, C, W, Y conjugate
  • Heptavalent pneumococcal conjugate
  • Measles, mumps, rubella, varicella


Catch-up Vaccinations:

  • Vaccines for children and adolescents aged 10 to 19 years are free under the National Immunisation Program.
  • This is to help those who didn’t get them in childhood to get up to date through a catch up schedule
    • Human papillomavirus (HPV) up to and including 25 years
    • dTpa, meningococcal ACWY up to and including 19 years
    • meningococcal B : children aged over 12 months to less than 2 years.

RSV Vaccine

Available RSV Vaccines and Monoclonal Antibodies in Australia
ProductTypeNotes
Abrysvo®Maternal + adult vaccineNIP-funded for pregnancy
Arexvy®Adult vaccinePrivate or state-funded
Beyfortus™ (nirsevimab)Monoclonal antibodyState/territory funded for eligible infants
Synagis®Monoclonal antibodyUsed in high-risk infants (specialist programs)

Who Should Not Receive RSV Vaccines or Antibodies

RSV vaccines or monoclonal antibodies should not be given to anyone with:

  • A history of anaphylaxis to a previous dose of the same product
  • Anaphylaxis to any component of the vaccine or antibody preparation

Possible Side Effects

Most reactions are mild and short-lived (1–2 days).

Common side effects include:

  • Pain or redness at the injection site
  • Fatigue
  • Headache
  • Muscle aches

RSV Prevention Recommendations (ATAGI)


Pneumococcal Vaccination

https://immunisationhandbook.health.gov.au/resources/publications/pneumococcal-vaccination-for-all-australians

new changes 1 July 2026.

  • Children aged <18 years: 20vPCV—Prevenar 20®.
  • Adults aged ≥18 years when eligible: 21vPCV—Capvaxive®.
  • outine adult age: reduced from 70 to 65 years.
  • Aboriginal and Torres Strait Islander adult age: reduced from 50 to 25 years.
  • Adult schedule: simplified to one 21vPCV dose for most eligible adults.
  • NIP access: requires Medicare eligibility.

Vaccines currently recommended

VaccineBrandRecommended populationRole
20vPCVPrevenar 20®Children aged <18 yearsRoutine childhood, risk-condition and catch-up schedules
21vPCVCapvaxive®Adults aged ≥18 years when eligible or clinically indicatedRoutine adult and adult risk-condition schedules
13vPCV, 15vPCV and 23vPPVVariousPrevious schedulesNo longer routinely used for new adult schedules;
previous doses influence timing of 21vPCV

Routine and risk-based schedule

Patient groupVaccineRecommended scheduleNIP-funded
All children20vPCV2, 4 and 12 monthsYes
ATSI infants20vPCV2, 4, 6 and 12 monthsYes
Infants
aged <12 months
with a risk condition
20vPCV2, 4, 6 and 12 monthsYes for specified conditions
Children
aged ≥12 months to <18 yrs
with a risk condition
20vPCVOne additional dose after completing the routine schedule, generally at diagnosisYes for specified conditions
Non-Indigenous adults
aged ≥65 years
21vPCVSingle doseYes
ATSI adults
aged ≥25 years
21vPCVSingle doseYes
Adults
aged ≥18 years with a risk condition
21vPCVSingle dose at diagnosis, or at age 18 if the condition was diagnosed during childhoodYes for specified conditions
Haematopoietic stem-cell transplant recipients20vPCV if <18; 21vPCV if ≥18Three-dose post-transplant course regardless of previous vaccinationRefer to specific HSCT schedule

General points

  • The first infant dose may be administered from six weeks of age.
  • If given at six weeks, the next dose remains due at four months.
  • Adults who receive 21vPCV before age 65 because of a risk condition do not require another routine dose at 65.
  • Aboriginal and Torres Strait Islander adults vaccinated with 21vPCV before developing a subsequent risk condition do not require another dose.
  • The need for additional or booster doses following 21vPCV has not been established, apart from specific circumstances such as HSCT.

Adults previously vaccinated against pneumococcus

Previous historyCurrent recommendation
No previous pneumococcal vaccineGive one dose of 21vPCV when eligible
Previous 13vPCV, 15vPCV, 20vPCV or 23vPPVGive one dose of 21vPCV at least 12 months after the most recent pneumococcal vaccine
Received 21vPCV before age 65 because of a risk conditionNo routine repeat dose at age 65
Received 21vPCV as an ATSI adult aged ≥25 yearsNo repeat dose solely because a risk condition is subsequently diagnosed
Previous HSCTThree-dose post-transplant schedule regardless of earlier pneumococcal vaccination

The previous routine adult schedule of 13vPCV followed by one or two doses of 23vPPV has been replaced by a single dose of 21vPCV for most eligible adults.

Medical risk conditions and NIP funding

Clinical recommendation and NIP funding are not identical. People with any condition below may be recommended vaccination, but only specified conditions are government funded.

CategoryConditionsNIP-funded
Previous invasive diseasePrevious invasive pneumococcal diseaseYes
Asplenia/hypospleniaSickle cell disease, other haemoglobinopathy, congenital or acquired asplenia, splenectomy or hypospleniaYes
Primary immunodeficiencyInborn errors of immunity, including symptomatic IgG subclass deficiency or isolated IgA deficiencyYes
Haematological malignancyLeukaemia, lymphoma and other haematological malignancyYes
TransplantationSolid-organ transplant or HSCTYes
HIVHIV infectionYes
Immunosuppressive treatmentCurrent, planned or anticipated immunosuppressive therapy where vaccine response is expectedNo
Non-haematological malignancyChemotherapy or radiotherapy, current or anticipatedNo
CSF leakProven or presumed CSF leak, cochlear implant or intracranial shuntYes
Suppurative respiratory diseaseSuppurative lung disease, bronchiectasis or cystic fibrosisYes
Chronic neonatal lung diseaseChronic lung disease of prematurityYes
COPDCOPD, including chronic bronchitis and emphysemaYes
Severe asthmaFrequent medical consultations or treatment with multiple medicationsNo
Interstitial lung diseaseInterstitial or fibrotic lung diseaseNo
Nephrotic syndromeRelapsing or persistent nephrotic syndromeYes
Chronic kidney diseaseeGFR <30 mL/min/1.73 m²Only if eGFR <15 or receiving dialysis
In-utero biological exposureInfant exposed to anti-CD20 therapy, such as rituximab, during pregnancyNo
Cardiac diseaseCongenital heart disease, coronary artery disease or congestive heart failureOnly if aged <5 years when commencing the schedule
Extreme prematurityBirth at <28 weeks gestationOnly if aged <5 years when commencing the schedule
Chromosomal/genetic conditionTrisomy 21 or another genetic condition increasing severe disease riskOnly if aged <5 years when commencing the schedule
Chronic liver diseaseProgressive liver dysfunction for >6 months, cirrhosis or other advanced liver diseaseYes
DiabetesType 1 or type 2 diabetesNo
SmokingCurrent or recent smokingNo
Harmful alcohol useAverage ≥100 g alcohol/week or ≥40 g alcohol/dayNo

Childhood transition and catch-up considerations

  • Children who commenced their routine schedule with 13vPCV or 15vPCV should complete the remaining scheduled doses with 20vPCV.
  • Healthy children who have already completed their routine PCV schedule with 13vPCV or 15vPCV generally do not require a supplementary 20vPCV dose.
  • A dose of 20vPCV given to a child with a risk condition should generally be:
    • at least eight weeks after the previous PCV dose; and
    • at least 12 months after a previous 23vPPV dose.

Queensland ATSI children

ATSI children in Queensland who completed their age-appropriate childhood schedule using only 13vPCV or 15vPCV are recommended:

  • One dose of 20vPCV at age four years; or
  • 12 months after the most recent PCV dose,

whichever is later.

If the child received one dose of 23vPPV after completing a 13vPCV/15vPCV schedule, give 20vPCV at least five years after that 23vPPV dose.

Children who completed their PCV schedule and subsequently received two doses of 23vPPV do not require a supplementary 20vPCV dose.

Co-administration

  • Pneumococcal vaccines may be administered at the same visit as influenza, COVID-19, Shingrix and other indicated non-live vaccines.
  • Use separate syringes and different injection sites.
  • If two injections are administered in the same limb, separate the sites by at least 2.5 cm.

Leave a Reply

This site uses Akismet to reduce spam. Learn how your comment data is processed.