This is a syndrome characterised by glomerulonephritis and respiratory disease together.
It is driven by a type 2 hypersensitivity reaction whereby IgG anti-basement membrane antibodies attach to the glomerulus to cause glomerulonephritis but can also react with the alveolar membrane to cause pulmonary haemorrhage.
The three features to remember are:
Haemoptysis
Haematuria
Anaemia
Treatment is with corticosteroids, but in some cases plasmapheresis to remove autoantibodies has shown great success.