HEADACHES,  NEUROLOGY

Tension Headache 


    Epidemiology & Demographics

    • Female predominance less marked than in migraine.
    • Commonly begins in young adulthood or later.
    • 50% lifetime prevalence; often coexists with migraine.

    Clinical Features

    FeatureTension-Type HeadacheMigraine
    Nature of PainDull, pressing, tight (“band-like”); non-pulsatileThrobbing, pulsatile
    SeverityMild to moderateModerate to severe
    LateralityBilateral (90%)Unilateral (typically temporal or retro-orbital)
    LocationFrontal, occipital, bitemporal, generalisedUnilateral, frontotemporal or occipital
    Systemic/Neurological SymptomsAbsentCommon (photophobia, phonophobia, nausea)
    AuraAbsentOften present (e.g., visual disturbances)
    Exacerbated by physical activityNoYes
    Associated SymptomsMay include photophobia, phonophobia (not both), rare nausea (no vomiting)Often includes nausea, vomiting, photophobia, phonophobia, osmophobia
    Duration30 minutes to 7 days4–72 hours
    CourseSpectrum: infrequent to chronic dailyEpisodic or chronic

    Precipitating & Aggravating Factors

    Tension-Type HeadacheMigraine
    – Stress (esp. at end of day)
    – Sleep deprivation or oversleeping
    – Sedentary lifestyle
    – Poor posture
    – Stress (onset or relief)
    – Hormonal changes (e.g., menstruation)
    – Bright light, strong odours
    – Skipping meals
    – Weather changes

    Pathophysiology Overview

    • Thought to involve peripheral myofascial nociception (episodic) and central sensitisation (chronic).
    • Lack of overt vascular or neurological features.

    Treatment Overview

    🟦 Acute Management – Infrequent TTH

    • First-line non-opioid analgesics (taken at onset):
    MedicationDoseMax in 24h
    Aspirin600–900 mg PO, q4–6h2 g
    Diclofenac potassium50 mg PO, q4–6h150 mg
    Ibuprofen400 mg PO, q4–6h2.4 g
    Naproxen500–750 mg PO, q6h1250 mg
    Paracetamol1000 mg PO, q4–6h4 g

    💡 Avoid opioids due to risk of dependence and rebound headache.


    🟦 General & Lifestyle Measures

    • Stress reduction (CBT, relaxation therapy)
    • Regular exercise, aerobic activity
    • Postural correction, ergonomic assessment
    • Avoidance of excessive alcohol and analgesic overuse
    • Address contributing factors: depression, anxiety, sleep hygiene
    • Tobacco cessation

    🟦 Non-Pharmacological Therapies

    • Cognitive behavioural therapy – effective for frequent TTH
    • Acupuncture – ≥6 sessions may benefit
    • Physiotherapy – especially with neck stretching/endurance program
    • Massage or mobilisation of cervical/paraspinal musculature

    Preventive Pharmacotherapy (for frequent or chronic TTH)

    First-line Preventives

    • Amitriptyline 10–75 mg nocte (max up to 200–250 mg in refractory cases)
    • Nortriptyline 10–75 mg nocte (fewer anticholinergic effects)

    Trial for 8 weeks, then review. Continue for 6 months if effective, followed by tapering.

    Alternatives

    • Mirtazapine 15–30 mg nocte, review at 8–12 weeks
    • Venlafaxine XR 75–150 mg in the morning with food

    Refractory Headache Strategy

    • Short trial (3-week) of naproxen 250–500 mg BD to break the analgesic dependency cycle
      • ⚠️ Do not repeat if ineffective

    🟫 Interventional Treatments (selected cases)

    • Trigger point injections (occiput, trapezius)
    • Myofascial release techniques
    • C1–C2 lateral joint injection (specialist referral only)

    🔄 Coexisting Migraine Consideration

    • TTH and migraine can coexist; distinguish overlapping features
    • Mixed-type headache sufferers may benefit from dual-pathway approaches (e.g., TCAs ± triptans PRN for migraine episodes)

    📌 Key Points

    Consider specialist referral if non-responsive to multiple prophylactic strategies or for interventional options.

    Tension-type headache is non-pulsatile, bilateral, and typically not aggravated by exertion.

    Management relies on lifestyle modification, non-opioid analgesia, and prophylaxis for chronic forms.

    Avoid medication overuse; address comorbid depression/anxiety.

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